General Cell Based Assays
Eurofins Discoverx PathHunter Human AGTR1 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human AGTR1 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure AGTR1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse HCRTR1 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse HCRTR1 β-Arrestin Stable Cell Pool Assay (CHO-K1) contains a stable engineered cell pool used to measure mHCRTR1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell pool vials, all required culture reagents for maintaining the cells in continuous culture, and detection reagents for running the assay.
Eurofins Discoverx PathHunter eXpress GPR109A CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0301E2CP2M)
The PathHunter GPR109A eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. nicotinic acid) based activation of GPR109A GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR109A and EA-tagged β-Arrestin-2. Activation of GPR109A stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GLP1R Total GPCR Internalization Assay, 2-Plate Kit. (93-1075E3CP5M)
The PathHunter GLP1R Total GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of GLP1R via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged GLP1R and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the GLP1R receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human CXCL11 (CXCR3) Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human CXCL11 (CXCR3) Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure CXCR3 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Sino Biological Human IL-1RAcP / IL-1R3 Protein (His Tag), Endotoxin-Free 100µg
A DNA sequence encoding the human IL1R3 (NP_002173.1) extracellular domain (Met 1-Glu 359) was expressed, fused with the a C-terminal polyhistidine tag.
Cayman Chemical CellBased Assay Buffer Tablet
Cell-Based Assay Buffer Tablet has been formulated and tested to work with Cayman’s Assay Kits. Detailed instructions for its use are contained in the respective Cayman Assay Kit booklet.
Medchemexpress LLC GNE-987 GSH linker-1 | 2417370-39-7 | C62H77F2N9O12S4 | 10MG
GNE-987 GSH linker-1 is a PROTAC-linker conjugate that pairs a BET-degrading warhead with a disulfide-containing glutathione-cleavable linker for use in PROTAC-antibody conjugate (PAC) research. It is intended as a research reagent for chemical biology studies involving targeted protein degradation and intracellular payload release.
- Enables targeted protein degradation when conjugated to antibodies.
- Contains a disulfide-based glutathione-cleavable linker for intracellular release.
- High chemical purity suitable for analytical and biological testing.
- Compatible with common solvents and recommended storage protocols.
- Applicable to studies of protein degradation pathways and PAC development.
Eurofins Discoverx PathHunter eXpress EDNRA CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0257E2CP0M)
The PathHunter EDNRA eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. endothelin-1) based activation of EDNRA GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged EDNRA and EA-tagged β-Arrestin-2. Activation of EDNRA stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Bioassay Systems EnzyFluo™ NADP/NADPH Assay Kit. For quantitative determination of NADP and NADPH and evaluation of drug effects on their metabolism (This product is a replacement for the discontinued product EFNP-100).
For quantitative determination of NADP and NADPH and evaluation of drug effects on their metabolism (This product is a replacement for the discontinued product EFNP-100). Key Features: Sensitive and accurate. Detection limit of 0.01 µM and linearity up to 1 µM NADP+/NADPH in 96-well plate assay. Convenient. The procedure involves adding a single working reagent, and reading the fluorescence at time zero and 30 min. Room temperature assay. High-throughput. Can be readily automated as a high-throughput 96-well plate assay for thousands of samples per day. Method: FL530/585nm. Samples: Cell, tissue extracts etc. Species: All. Procedure: Assay takes 30 min. Kit size: 100 tests. Detection limit: 0.01 µM.
Creative Biomart Follitropin
The product is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin which consists of two non-covalently linked non-identical glycoproteins designated as the alpha- and beta- subunits The alpha- and beta- subunits have 92 and 111 amino acids The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glycosylated at Asn 7 and Asn 24 The product beta is produced in genetically engineered CHO
Eurofins Discoverx PathHunter Human PTGER4 Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human PTGER4 Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure PTGER4 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human NPBWR2 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human NPBWR2 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure NPBWR2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse MIP-3 alpha (CCR6) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse MIP-3 alpha (CCR6) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure mCCR6 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human Heregulin β1 (EGFR/ErbB3) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human Heregulin β1 (EGFR/ErbB3) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of EGFR/ErbB3. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.